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Inhibition of the potassium channel Kv1.3 reduces infarction and inflammation in ischemic stroke
OBJECTIVE: Inhibitors of the voltage‐gated K(+) channel Kv1.3 are currently in development as immunomodulators for the treatment of autoimmune diseases. As Kv1.3 is also expressed on microglia and has been shown to be specifically up‐regulated on “M1‐like” microglia, we here tested the therapeutic h...
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| Опубликовано в: : | Ann Clin Transl Neurol |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
John Wiley and Sons Inc.
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5817832/ https://ncbi.nlm.nih.gov/pubmed/29468176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.513 |
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