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Inhibition of the potassium channel Kv1.3 reduces infarction and inflammation in ischemic stroke
OBJECTIVE: Inhibitors of the voltage‐gated K(+) channel Kv1.3 are currently in development as immunomodulators for the treatment of autoimmune diseases. As Kv1.3 is also expressed on microglia and has been shown to be specifically up‐regulated on “M1‐like” microglia, we here tested the therapeutic h...
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| Publicado no: | Ann Clin Transl Neurol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5817832/ https://ncbi.nlm.nih.gov/pubmed/29468176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.513 |
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