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Role and targeting of anaplastic lymphoma kinase in cancer

Anaplastic lymphoma kinase (ALK) gene activation is involved in the carcinogenesis process of several human cancers such as anaplastic large cell lymphoma, lung cancer, inflammatory myofibroblastic tumors and neuroblastoma, as a consequence of fusion with other oncogenes (NPM, EML4, TIM, etc) or gen...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cancer
Hauptverfasser: Della Corte, Carminia Maria, Viscardi, Giuseppe, Di Liello, Raimondo, Fasano, Morena, Martinelli, Erika, Troiani, Teresa, Ciardiello, Fortunato, Morgillo, Floriana
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817803/
https://ncbi.nlm.nih.gov/pubmed/29455642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-018-0776-2
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