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Role and targeting of anaplastic lymphoma kinase in cancer

Anaplastic lymphoma kinase (ALK) gene activation is involved in the carcinogenesis process of several human cancers such as anaplastic large cell lymphoma, lung cancer, inflammatory myofibroblastic tumors and neuroblastoma, as a consequence of fusion with other oncogenes (NPM, EML4, TIM, etc) or gen...

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Bibliographic Details
Published in:Mol Cancer
Main Authors: Della Corte, Carminia Maria, Viscardi, Giuseppe, Di Liello, Raimondo, Fasano, Morena, Martinelli, Erika, Troiani, Teresa, Ciardiello, Fortunato, Morgillo, Floriana
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817803/
https://ncbi.nlm.nih.gov/pubmed/29455642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-018-0776-2
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