Therapeutic value of EGFR inhibition in CRC and NSCLC: 15 years of clinical evidence

Epidermal growth factor receptor (EGFR) plays a key role in tumour evolution, proliferation and immune evasion, and is one of the most important targets for biological therapy, especially for non-small-cell lung cancer (NSCLC) and colorectal cancer (CRC). In the past 15 years, several EGFR antagonis...

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Bibliographic Details
Published in:ESMO Open
Main Authors: Troiani, Teresa, Napolitano, Stefania, Della Corte, Carminia Maria, Martini, Giulia, Martinelli, Erika, Morgillo, Floriana, Ciardiello, Fortunato
Format: Artigo
Language:Inglês
Published: BMJ Publishing Group 2016
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070253/
https://ncbi.nlm.nih.gov/pubmed/27843640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/esmoopen-2016-000088
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