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Antitumor efficacy of triple monoclonal antibody inhibition of epidermal growth factor receptor (EGFR) with MM151 in EGFR-dependent and in cetuximab-resistant human colorectal cancer cells
PURPOSE: We investigated the effect of triple monoclonal antibody inhibition of EGFR to overcome acquired resistance to first generation of anti-EGFR inhibitors. EXPERIMENTAL DESIGN: MM151 is a mixture of three different monoclonal IgG1 antibodies directed toward three different, non-overlapping, ep...
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| Yayımlandı: | Oncotarget |
|---|---|
| Asıl Yazarlar: | , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Impact Journals LLC
2017
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5669927/ https://ncbi.nlm.nih.gov/pubmed/29137301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19797 |
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