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Mechanisms of resistance to EGFR-targeted drugs: lung cancer

Despite the improvement in clinical outcomes derived by the introduction of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (EGFR-TKIs) in the treatment of patients with advanced non-small cell lung cancer (NSCLC) whose tumours harbour EGFR-activating mutations, prognosis remains...

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Bibliographic Details
Published in:ESMO Open
Main Authors: Morgillo, Floriana, Della Corte, Carminia Maria, Fasano, Morena, Ciardiello, Fortunato
Format: Artigo
Language:Inglês
Published: BMJ Publishing Group 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5070275/
https://ncbi.nlm.nih.gov/pubmed/27843613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/esmoopen-2016-000060
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