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Molecular genetics and cellular events of K-Ras-driven tumorigenesis

Cellular transformation and the accumulation of genomic instability are the two key events required for tumorigenesis. K-Ras (Kirsten-rat sarcoma viral oncogene homolog) is a prominent oncogene that has been proven to drive tumorigenesis. K-Ras also modulates numerous genetic regulatory mechanisms a...

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Bibliografiska uppgifter
I publikationen:Oncogene
Huvudupphovsmän: Jinesh, G G, Sambandam, V, Vijayaraghavan, S, Balaji, K, Mukherjee, S
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5817384/
https://ncbi.nlm.nih.gov/pubmed/29059163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2017.377
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