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Targeting K-Ras and apoptosis-driven cellular transformation in cancer

Cellular transformation is a major event that helps cells to evade apoptosis, genomic instability checkpoints, and immune surveillance to initiate tumorigenesis and to promote progression by cancer stem cell expansion. However, the key molecular players that govern cellular transformation and ways t...

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Bibliographische Detailangaben
Veröffentlicht in:Cell Death Discov
Hauptverfasser: Godwin, Isha, Anto, Nikhil Ponnoor, Bava, Smitha V., Babu, Mani Shankar, Jinesh, Goodwin G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8047025/
https://ncbi.nlm.nih.gov/pubmed/33854056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-021-00457-5
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