Novel signaling axis for ROS generation during K-Ras-induced cellular transformation

Reactive oxygen species (ROS) are well known to be involved in oncogene-mediated cellular transformation. However, the regulatory mechanisms underlying ROS generation in oncogene-transformed cells are unclear. In the present study, we found that oncogenic K-Ras induces ROS generation through activat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Park, M-T, Kim, M-J, Suh, Y, Kim, R-K, Kim, H, Lim, E-J, Yoo, K-C, Lee, G-H, Kim, Y-H, Hwang, S-G, Yi, J-M, Lee, S-J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
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Original Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4085525/
https://ncbi.nlm.nih.gov/pubmed/24632950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.34
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