Involvement of mitophagy in oncogenic K-Ras-induced transformation: Overcoming a cellular energy deficit from glucose deficiency

Although mitochondrial impairment has often been implicated in carcinogenesis, the mechanisms of its development in cancer remain unknown. We report here that autophagy triggered by oncogenic K-Ras mediates functional loss of mitochondria during cell transformation to overcome an energy deficit resu...

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Hlavní autoři: Kim, June-Hyung, Kim, Hee Young, Lee, Young-Kyoung, Yoon, Young-Sil, Xu, Wei Guang, Yoon, Joon-Kee, Choi, Sung-E, Ko, Young-Gyu, Kim, Min-Jung, Lee, Su-Jae, Wang, Hee-Jung, Yoon, Gyesoon
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2011
Témata:
Basic Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242615/
https://ncbi.nlm.nih.gov/pubmed/21738012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.10.16643
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