Involvement of mitophagy in oncogenic K-Ras-induced transformation: Overcoming a cellular energy deficit from glucose deficiency

Although mitochondrial impairment has often been implicated in carcinogenesis, the mechanisms of its development in cancer remain unknown. We report here that autophagy triggered by oncogenic K-Ras mediates functional loss of mitochondria during cell transformation to overcome an energy deficit resu...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Kim, June-Hyung, Kim, Hee Young, Lee, Young-Kyoung, Yoon, Young-Sil, Xu, Wei Guang, Yoon, Joon-Kee, Choi, Sung-E, Ko, Young-Gyu, Kim, Min-Jung, Lee, Su-Jae, Wang, Hee-Jung, Yoon, Gyesoon
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Landes Bioscience 2011
Aiheet:
Basic Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242615/
https://ncbi.nlm.nih.gov/pubmed/21738012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.10.16643
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