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How do K-RAS-activated cells evade cellular defense mechanisms?

Lung adenocarcinomas, like other cancers, develop through the accumulation of epigenetic and genetic alterations. Numerous studies have shown that K-RAS mutation is among the most important early events in carcinogenesis of the lung. However, it is also well established that growth-stimulating signa...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Lee, Y-S, Bae, S-C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4761642/
https://ncbi.nlm.nih.gov/pubmed/25961920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2015.153
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