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Allosteric Pathways in Nuclear Receptors – Potential Targets for Drug Design
The nuclear receptor family of transcription factor proteins mediate endocrine function and play critical roles in development, physiology and pharmacology. Malfunctioning nuclear receptors are associated with several disease states. The functional activity of nuclear receptors is regulated by small...
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| Publicado no: | Pharmacol Ther |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5817003/ https://ncbi.nlm.nih.gov/pubmed/29080700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2017.10.014 |
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