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The Promiscuity of Allosteric Regulation of Nuclear Receptors by Retinoid X Receptor

The promiscuous protein retinoid X receptor (RXR) displays essential allosteric regulation of several members in the nuclear hormone receptor superfamily via heterodimerization and (anti)cooperative binding of cognate ligands. Here, the structural basis of the positive allostery of RXR and constitut...

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Detalhes bibliográficos
Publicado no:J Phys Chem B
Main Authors: Clark, Alexander K., Wilder, J. Heath, Grayson, Aaron W., Johnson, Quentin R., Lindsay, Richard J., Nellas, Ricky B., Fernandez, Elias J., Shen, Tongye
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5001894/
https://ncbi.nlm.nih.gov/pubmed/27110634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.6b02057
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