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Allosteric Pathways in Nuclear Receptors – Potential Targets for Drug Design
The nuclear receptor family of transcription factor proteins mediate endocrine function and play critical roles in development, physiology and pharmacology. Malfunctioning nuclear receptors are associated with several disease states. The functional activity of nuclear receptors is regulated by small...
Guardat en:
| Publicat a: | Pharmacol Ther |
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| Autor principal: | |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5817003/ https://ncbi.nlm.nih.gov/pubmed/29080700 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2017.10.014 |
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