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Assembly mechanism of the CARMA1–BCL10–MALT1–TRAF6 signalosome

The CARMA1–BCL10–MALT1 (CBM) signalosome is a central mediator of T cell receptor and B cell receptor-induced NF-κB signaling that regulates multiple lymphocyte functions. While caspase-recruitment domain (CARD) membrane-associated guanylate kinase (MAGUK) protein 1 (CARMA1) nucleates B cell lymphom...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: David, Liron, Li, Yang, Ma, Jun, Garner, Ethan, Zhang, Xinzheng, Wu, Hao
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5816215/
https://ncbi.nlm.nih.gov/pubmed/29382759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1721967115
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