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Structural Insights into the Assembly of CARMA1 and BCL10
The CBM complex (CARMA1, BCL10 and MALT1) plays a crucial role in B and T lymphocyte activation. CARMA1 serves as a scaffold for BCL10, MALT1 and other effector proteins and regulates various signaling pathways related to the immune response. The assembly of CARMA1 and BCL10 is mediated through a CA...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3411838/ https://ncbi.nlm.nih.gov/pubmed/22880103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042775 |
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