Structural Architecture of the CARMA1/Bcl10/MALT1 Signalosome: Nucleation-Induced Filamentous Assembly

The CARMA1/Bcl10/MALT1 (CBM) signalosome mediates antigen receptor-induced NF-κB signaling to regulate multiple lymphocyte functions. While CARMA1 and Bcl10 contain caspase recruitment domains (CARDs), MALT1 is a paracaspase with structural similarity to caspases. Here we show that the reconstituted...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Qiao, Qi, Yang, Chenghua, Zheng, Chao, Fontán, Lorena, David, Liron, Yu, Xiong, Bracken, Clay, Rosen, Monica, Melnick, Ari, Egelman, Edward H., Wu, Hao
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929958/
https://ncbi.nlm.nih.gov/pubmed/24074955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.08.032
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados