COP9 signalosome controls the Carma1–Bcl10–Malt1 complex upon T-cell stimulation

The Carma1–Bcl10–Malt1 (CBM) complex connects T-cell receptor (TCR) signalling to the canonical IκB kinase (IKK)/NF (nuclear factor)-κB pathway. Earlier studies have indicated that the COP9 signalosome (CSN), a pleiotropic regulator of the ubiquitin/26S proteasome system, controls antigen responses...

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Detalhes bibliográficos
Main Authors: Welteke, Verena, Eitelhuber, Andrea, Düwel, Michael, Schweitzer, Katrin, Naumann, Michael, Krappmann, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Scientific Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711841/
https://ncbi.nlm.nih.gov/pubmed/19444310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2009.64
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