AIP augments CARMA1-BCL10-MALT1 complex formation to facilitate NF-κB signaling upon T cell activation

BACKGROUND: The CARMA1-BCL10-MALT1 (CBM) complex bridges T cell receptor (TCR) signaling to the canonical IκB kinase (IKK)/NF-κB pathway. The CBM complex constitutes a signaling cluster of more than 1 Mio Dalton. Little is known about factors that facilitate the rapid assembly and maintenance of thi...

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Bibliografiske detaljer
Udgivet i:Cell Commun Signal
Main Authors: Schimmack, Gisela, Eitelhuber, Andrea C, Vincendeau, Michelle, Demski, Katrin, Shinohara, Hisaaki, Kurosaki, Tomohiro, Krappmann, Daniel
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Short Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222456/
https://ncbi.nlm.nih.gov/pubmed/25245034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-014-0049-7
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