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Type II-C CRISPR-Cas9 Biology, Mechanism and Application

Genome editing technologies have been revolutionized by the discovery of prokaryotic RNA-guided defense system called CRISPR-Cas. Cas9, a single effector protein found in type II CRISPR systems, has been at the heart of this genome editing revolution. Nearly half of the Cas9s discovered so far belon...

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Bibliographic Details
Published in:ACS Chem Biol
Main Authors: Mir, Aamir, Edraki, Alireza, Lee, Jooyoung, Sontheimer, Erik J.
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5815938/
https://ncbi.nlm.nih.gov/pubmed/29202216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b00855
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