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Surrogate Wnt agonists that phenocopy canonical Wnt/β-catenin signaling
Wnts modulate cell proliferation, differentiation and stem cell self-renewal, by inducing β-catenin dependent signaling through Frizzled (Fzd) and Lrp5/6 to regulate cell fate decisions, and the growth and repair of a multitude of tissues(1). The 19 mammalian Wnts interact promiscuously with the 10...
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| 出版年: | Nature |
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| 主要な著者: | , , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5815871/ https://ncbi.nlm.nih.gov/pubmed/28467818 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature22306 |
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