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A dual function for canonical Wnt/β-catenin signaling in the developing mammalian cochlea

The canonical Wnt/β-catenin signaling pathway is known to play crucial roles in organogenesis by regulating both proliferation and differentiation. In the inner ear, this pathway has been shown to regulate the size of the otic placode from which the cochlea will arise; however, direct activity of ca...

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Detalhes bibliográficos
Main Authors: Jacques, Bonnie E., Puligilla, Chandrakala, Weichert, Rachel M., Ferrer-Vaquer, Anna, Hadjantonakis, Anna-Katerina, Kelley, Matthew W., Dabdoub, Alain
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3509733/
https://ncbi.nlm.nih.gov/pubmed/23132246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.080358
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