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A dual function for canonical Wnt/β-catenin signaling in the developing mammalian cochlea

The canonical Wnt/β-catenin signaling pathway is known to play crucial roles in organogenesis by regulating both proliferation and differentiation. In the inner ear, this pathway has been shown to regulate the size of the otic placode from which the cochlea will arise; however, direct activity of ca...

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Autors principals: Jacques, Bonnie E., Puligilla, Chandrakala, Weichert, Rachel M., Ferrer-Vaquer, Anna, Hadjantonakis, Anna-Katerina, Kelley, Matthew W., Dabdoub, Alain
Format: Artigo
Idioma:Inglês
Publicat: Company of Biologists 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3509733/
https://ncbi.nlm.nih.gov/pubmed/23132246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.080358
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