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Transcriptional response to Wnt activation regulates the regenerative capacity of the mammalian cochlea
Lack of sensory hair cell (HC) regeneration in mammalian adults is a major contributor to hearing loss. In contrast, the neonatal mouse cochlea retains a transient capacity for regeneration, and forced Wnt activation in neonatal stages promotes supporting cell (SC) proliferation and induction of ect...
Gespeichert in:
| Veröffentlicht in: | Development |
|---|---|
| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Company of Biologists Ltd
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6288390/ https://ncbi.nlm.nih.gov/pubmed/30389848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.166579 |
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