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Risky Repair: DNA-protein Crosslinks Formed by Mitochondrial Base Excision DNA Repair Enzymes Acting on Free Radical Lesions

Oxygen is both necessary and dangerous for the aerobic cell function. ATP is most efficiently made by the electron transport chain, which requires oxygen as an electron acceptor. However, the presence of oxygen, and to some extent the respiratory chain itself, poses a danger to cellular components....

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Detalhes bibliográficos
Publicado no:Free Radic Biol Med
Main Authors: Caston, Rachel Audrey, Demple, Bruce
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5815828/
https://ncbi.nlm.nih.gov/pubmed/27867099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2016.11.025
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