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Risky Repair: DNA-protein Crosslinks Formed by Mitochondrial Base Excision DNA Repair Enzymes Acting on Free Radical Lesions
Oxygen is both necessary and dangerous for the aerobic cell function. ATP is most efficiently made by the electron transport chain, which requires oxygen as an electron acceptor. However, the presence of oxygen, and to some extent the respiratory chain itself, poses a danger to cellular components....
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| Published in: | Free Radic Biol Med |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5815828/ https://ncbi.nlm.nih.gov/pubmed/27867099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2016.11.025 |
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