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When DNA Repair Goes Wrong: BER-Generated DNA-protein Crosslinks to Oxidative Lesions
Free radicals generate an array of DNA lesions affecting all parts of the molecule. The damage to deoxyribose receives less attention than base damage, even though the former accounts for ~20% of the total. Oxidative deoxyribose fragments (e.g., 3’-phosphoglycolate esters) are removed by the Ape1 AP...
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| Publicado no: | DNA Repair (Amst) |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6420214/ https://ncbi.nlm.nih.gov/pubmed/27264558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2016.05.014 |
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