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When DNA Repair Goes Wrong: BER-Generated DNA-protein Crosslinks to Oxidative Lesions

Free radicals generate an array of DNA lesions affecting all parts of the molecule. The damage to deoxyribose receives less attention than base damage, even though the former accounts for ~20% of the total. Oxidative deoxyribose fragments (e.g., 3’-phosphoglycolate esters) are removed by the Ape1 AP...

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Bibliografiske detaljer
Udgivet i:DNA Repair (Amst)
Main Authors: Quiñones, Jason Luis, Demple, Bruce
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420214/
https://ncbi.nlm.nih.gov/pubmed/27264558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2016.05.014
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