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When DNA Repair Goes Wrong: BER-Generated DNA-protein Crosslinks to Oxidative Lesions
Free radicals generate an array of DNA lesions affecting all parts of the molecule. The damage to deoxyribose receives less attention than base damage, even though the former accounts for ~20% of the total. Oxidative deoxyribose fragments (e.g., 3’-phosphoglycolate esters) are removed by the Ape1 AP...
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| Pubblicato in: | DNA Repair (Amst) |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6420214/ https://ncbi.nlm.nih.gov/pubmed/27264558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2016.05.014 |
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