Expression of cell cycle regulators and frequency of TP53 mutations in high risk gastrointestinal stromal tumors prior to adjuvant imatinib treatment

Despite of multitude investigations no reliable prognostic immunohistochemical biomarkers in GIST have been established so far with added value to predict the recurrence risk of high risk GIST besides mitotic count, primary location and size. In this study, we analyzed the prognostic relevance of ei...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Ihle, Michaela Angelika, Huss, Sebastian, Jeske, Wiebke, Hartmann, Wolfgang, Merkelbach-Bruse, Sabine, Schildhaus, Hans-Ulrich, Büttner, Reinhard, Sihto, Harri, Sundby Hall, Kirsten, Eriksson, Mikael, Reichardt, Peter, Joensuu, Heikki, Wardelmann, Eva
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5815598/
https://ncbi.nlm.nih.gov/pubmed/29451912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0193048
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