Effect of KIT and PDGFRA Mutations on Survival in Patients With Gastrointestinal Stromal Tumors Treated With Adjuvant Imatinib: An Exploratory Analysis of a Randomized Clinical Trial

IMPORTANCE: Little is known about whether the duration of adjuvant imatinib influences the prognostic significance of KIT proto-oncogene receptor tyrosine kinase (KIT) and platelet-derived growth factor receptor α (PDGFRA) mutations. OBJECTIVE: To investigate the effect of KIT and PDGFRA mutations o...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:JAMA Oncol
मुख्य लेखकों: Joensuu, Heikki, Wardelmann, Eva, Sihto, Harri, Eriksson, Mikael, Sundby Hall, Kirsten, Reichardt, Annette, Hartmann, Jörg T., Pink, Daniel, Cameron, Silke, Hohenberger, Peter, Al-Batran, Salah-Eddin, Schlemmer, Marcus, Bauer, Sebastian, Nilsson, Bengt, Kallio, Raija, Junnila, Jouni, Vehtari, Aki, Reichardt, Peter
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Medical Association 2017
विषय:
Original Investigation
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5470395/
https://ncbi.nlm.nih.gov/pubmed/28334365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2016.5751
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