Expression of cell cycle regulators and frequency of TP53 mutations in high risk gastrointestinal stromal tumors prior to adjuvant imatinib treatment

Despite of multitude investigations no reliable prognostic immunohistochemical biomarkers in GIST have been established so far with added value to predict the recurrence risk of high risk GIST besides mitotic count, primary location and size. In this study, we analyzed the prognostic relevance of ei...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Ihle, Michaela Angelika, Huss, Sebastian, Jeske, Wiebke, Hartmann, Wolfgang, Merkelbach-Bruse, Sabine, Schildhaus, Hans-Ulrich, Büttner, Reinhard, Sihto, Harri, Sundby Hall, Kirsten, Eriksson, Mikael, Reichardt, Peter, Joensuu, Heikki, Wardelmann, Eva
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2018
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5815598/
https://ncbi.nlm.nih.gov/pubmed/29451912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0193048
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