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Tumor-infiltrating lymphocytes and outcome in Merkel cell carcinoma, a virus-associated cancer

An intense immune infiltrate, enriched in T cells, is associated with the presence of Merkel cell polyomavirus (MCPyV) DNA in Merkel cell carcinoma (MCC), a rare skin cancer. High tumor-infiltrating T-cell counts are associated with favorable survival regardless of the tumor MCPyV status. Hence, boo...

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Bibliographic Details
Main Authors: Sihto, Harri, Joensuu, Heikki
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3518523/
https://ncbi.nlm.nih.gov/pubmed/23243614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.21120
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