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The N Terminus of the OB Domain of Telomere Protein TPP1 Is Critical for Telomerase Action
Telomerase recruitment to telomeres and enzymatic processivity are mediated by TPP1, an essential component of telomere integrity and telomerase function. A surface on the OB domain of TPP1 called the TEL patch is critical for TPP1’s telomerase-associated functions. Here, we identify a separate regi...
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| Publicado no: | Cell Rep |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5815312/ https://ncbi.nlm.nih.gov/pubmed/29386102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.01.012 |
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