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La-related protein 1 (LARP1) repression of TOP mRNA translation is mediated through its cap-binding domain and controlled by an adjacent regulatory region

Cell growth is a complex process shaped by extensive and coordinated changes in gene expression. Among these is the tightly regulated translation of a family of growth-related mRNAs defined by a 5′ terminal oligopyrimidine (TOP) motif. TOP mRNA translation is partly controlled via the eukaryotic ini...

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Pubblicato in:Nucleic Acids Res
Autori principali: Philippe, Lucas, Vasseur, Jean-Jacques, Debart, Françoise, Thoreen, Carson C
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814973/
https://ncbi.nlm.nih.gov/pubmed/29244122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1237
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