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Capturing the Mechanism Underlying TOP mRNA Binding to LARP1
The RNA-binding protein La-related protein 1 (LARP1) plays a central role in ribosome biosynthesis. Its C-terminal DM15 region binds the 7-methylguanosine (m(7)G) cap and 5’ terminal oligopyrimidine (TOP) motif characteristic of transcripts encoding ribosomal proteins and translation factors. Under...
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| 出版年: | Structure |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7269035/ https://ncbi.nlm.nih.gov/pubmed/31676287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2019.10.006 |
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