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Global analysis of LARP1 translation targets reveals tunable and dynamic features of 5′ TOP motifs
Terminal oligopyrimidine (TOP) motifs are sequences at the 5′ ends of mRNAs that link their translation to the mTOR Complex 1 (mTORC1) nutrient-sensing signaling pathway. They are commonly regarded as discrete elements that reside on ∼100 mRNAs that mostly encode translation factors. However, the fu...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7071917/ https://ncbi.nlm.nih.gov/pubmed/32094190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1912864117 |
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