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DNMT3A in haematological malignancies

DNA methylation patterns are disrupted in various malignancies, suggesting a role in the development of cancer, but genetic aberrations directly linking the DNA methylation machinery to malignancies were rarely observed, so this association remained largely correlative. Recently, however, mutations...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Nat Rev Cancer
Hauptverfasser: Yang, Liubin, Rau, Rachel, Goodell, Margaret A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814392/
https://ncbi.nlm.nih.gov/pubmed/25693834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3895
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