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DNMT3A in haematological malignancies

DNA methylation patterns are disrupted in various malignancies, suggesting a role in the development of cancer, but genetic aberrations directly linking the DNA methylation machinery to malignancies were rarely observed, so this association remained largely correlative. Recently, however, mutations...

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Detalhes bibliográficos
Publicado no:Nat Rev Cancer
Main Authors: Yang, Liubin, Rau, Rachel, Goodell, Margaret A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5814392/
https://ncbi.nlm.nih.gov/pubmed/25693834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrc3895
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