A carregar...
Mechanism-based Inhibitors of the Human Sirtuin 5 Deacylase: Structure–Activity Relationship, Biostructural, and Kinetic Insight
The sirtuin enzymes are important regulatory deacylases in a variety of biochemical contexts and may therefore be potential therapeutic targets through either activation or inhibition by small molecules. Here, we describe the discovery of the most potent inhibitor of sirtuin 5 (SIRT5) reported to da...
Na minha lista:
| Publicado no: | Angew Chem Int Ed Engl |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5814306/ https://ncbi.nlm.nih.gov/pubmed/29044784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201709050 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|