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Activation of Grm1 expression by mutated BRaf (V600E) in vitro and in vivo
Our laboratory previously showed that ectopic expression of Grm1 is sufficient to induce spontaneous melanoma formation with 100% penetrance in transgenic mouse model, TG-3, which harbors wild-type BRaf. Studies identified Grm1 expression in human melanoma cell lines and primary to secondary metasta...
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| 出版年: | Oncotarget |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Impact Journals LLC
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5814180/ https://ncbi.nlm.nih.gov/pubmed/29464040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23637 |
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