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Altered Repolarization Reserve in Failing Rabbit Ventricular Myocytes: Calcium and Beta-adrenergic Effects on Delayed and Inward Rectifier Potassium Currents

BACKGROUND: Electrophysiological remodeling and increased susceptibility for cardiac arrhythmias are hallmarks of heart failure (HF). Ventricular action potential (AP) duration (APD) is typically prolonged in HF, with reduced repolarization reserve. However, underlying K(+) current changes are often...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Circ Arrhythm Electrophysiol
Main Authors: Hegyi, Bence, Bossuyt, Julie, Ginsburg, Kenneth S., Mendoza, Lynette M., Talken, Linda, Ferrier, William T., Pogwizd, Steven M., Izu, Leighton T., Chen-Izu, Ye, Bers, Donald M.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2018
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5813707/
https://ncbi.nlm.nih.gov/pubmed/29437761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCEP.117.005852
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