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Bone marrow mesenchymal stem cell-derived exosomal miR-21 protects C-kit(+) cardiac stem cells from oxidative injury through the PTEN/PI3K/Akt axis

Stem cell (SC) therapy for ischemic cardiomyopathy is hampered by poor survival of the implanted cells. Recently, SC-derived exosomes have been shown to facilitate cell proliferation and survival by transporting various proteins and non-coding RNAs (such as microRNAs and lncRNAs). In this study, miR...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Shi, Bei, Wang, Yan, Zhao, Ranzhun, Long, Xianping, Deng, Wenwen, Wang, Zhenglong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5812567/
https://ncbi.nlm.nih.gov/pubmed/29444190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0191616
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