miR-21 increases c-kit(+) cardiac stem cell proliferation in vitro through PTEN/PI3K/Akt signaling

The low survival rate of cardiac stem cells (CSCs) in the ischemic myocardium is one of the obstacles in ischemic cardiomyopathy cell therapy. The MicroRNA (miR)-21 and one of its target protein, the tensin homolog deleted on chromosome ten (PTEN), contributes to the proliferation of many kinds of t...

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Detalhes bibliográficos
Publicado no:PeerJ
Main Authors: Shi, Bei, Deng, Wenwen, Long, Xianping, Zhao, Ranzun, Wang, Yan, Chen, Wenming, Xu, Guanxue, Sheng, Jin, Wang, Dongmei, Cao, Song
Formato: Artigo
Idioma:Inglês
Publicado em: PeerJ Inc. 2017
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5289448/
https://ncbi.nlm.nih.gov/pubmed/28168101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.2859
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