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Modelling and simulation of biased agonism dynamics at a G protein-coupled receptor
Theoretical models of G protein-coupled receptor (GPCR) concentration-response relationships often assume an agonist producing a single functional response via a single active state of the receptor. These models have largely been analysed assuming steady-state conditions. There is now much experimen...
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| Udgivet i: | J Theor Biol |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Elsevier
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5811930/ https://ncbi.nlm.nih.gov/pubmed/29337260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtbi.2018.01.010 |
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