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Molecular determinants of Guanylate Cyclase Activating Protein subcellular distribution in photoreceptor cells of the retina

Retinal guanylate cyclase (RetGC) and guanylate cyclase activating proteins (GCAPs) play an important role during the light response in photoreceptor cells. Mutations in these proteins are linked to distinct forms of blindness. RetGC and GCAPs exert their role at the ciliary outer segment where phot...

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Publicat a:Sci Rep
Autors principals: López-Begines, Santiago, Plana-Bonamaisó, Anna, Méndez, Ana
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811540/
https://ncbi.nlm.nih.gov/pubmed/29440717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20893-1
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