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Functional EF-Hands in Neuronal Calcium Sensor GCAP2 Determine Its Phosphorylation State and Subcellular Distribution In Vivo, and Are Essential for Photoreceptor Cell Integrity
The neuronal calcium sensor proteins GCAPs (guanylate cyclase activating proteins) switch between Ca(2+)-free and Ca(2+)-bound conformational states and confer calcium sensitivity to guanylate cyclase at retinal photoreceptor cells. They play a fundamental role in light adaptation by coupling the ra...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4109901/ https://ncbi.nlm.nih.gov/pubmed/25058152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004480 |
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