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Molecular determinants of Guanylate Cyclase Activating Protein subcellular distribution in photoreceptor cells of the retina

Retinal guanylate cyclase (RetGC) and guanylate cyclase activating proteins (GCAPs) play an important role during the light response in photoreceptor cells. Mutations in these proteins are linked to distinct forms of blindness. RetGC and GCAPs exert their role at the ciliary outer segment where phot...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: López-Begines, Santiago, Plana-Bonamaisó, Anna, Méndez, Ana
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811540/
https://ncbi.nlm.nih.gov/pubmed/29440717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20893-1
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