The Function of Guanylate Cyclase 1 and Guanylate Cyclase 2 in Rod and Cone Photoreceptors

Retinal guanylate cyclases 1 and 2 (GC1 and GC2) are responsible for synthesis of cyclic GMP in rods and cones, but their individual contributions to phototransduction are unknown. We report here that the deletion of both GC1 and GC2 rendered rod and cone photoreceptors nonfunctional and unstable. I...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Baehr, Wolfgang, Karan, Sukanya, Maeda, Tadao, Luo, Dong-Gen, Li, Sha, Darin Bronson, J., Watt, Carl B., Yau, King-Wai, Frederick, Jeanne M., Palczewski, Krzysztof
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2007
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2043484/
https://ncbi.nlm.nih.gov/pubmed/17255100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M610369200
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