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The Function of Guanylate Cyclase 1 and Guanylate Cyclase 2 in Rod and Cone Photoreceptors

Retinal guanylate cyclases 1 and 2 (GC1 and GC2) are responsible for synthesis of cyclic GMP in rods and cones, but their individual contributions to phototransduction are unknown. We report here that the deletion of both GC1 and GC2 rendered rod and cone photoreceptors nonfunctional and unstable. I...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Baehr, Wolfgang, Karan, Sukanya, Maeda, Tadao, Luo, Dong-Gen, Li, Sha, Darin Bronson, J., Watt, Carl B., Yau, King-Wai, Frederick, Jeanne M., Palczewski, Krzysztof
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2007
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2043484/
https://ncbi.nlm.nih.gov/pubmed/17255100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M610369200
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