Pilot Study of Delayed ICOS/ICOS-L Blockade With αCD40 to Modulate Pathogenic Alloimmunity in a Primate Cardiac Allograft Model

BACKGROUND: Inducible costimulator (ICOS) is rapidly upregulated with T-cell stimulation and may represent an escape pathway for T-cell costimulation in the setting of CD40/CD154 costimulation blockade. Induction treatment exhibited no efficacy in a primate renal allograft model, but rodent transpla...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Transplant Direct
Egile Nagusiak: O’Neill, Natalie A., Zhang, Tianshu, Braileanu, Gheorghe, Cheng, Xiangfei, Hershfeld, Alena, Sun, Wenji, Reimann, Keith A., Dahi, Sia, Kubicki, Natalia, Hassanein, Wessam, Laird, Christopher, Cimeno, Arielle, Azimzadeh, Agnes M., Pierson, Richard N.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Lippincott Williams & Wilkins 2018
Gaiak:
Basic Science
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5811273/
https://ncbi.nlm.nih.gov/pubmed/29464205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TXD.0000000000000761
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