Comparative Evaluation of αCD40 (2C10R4) and αCD154 (5C8H1 and IDEC-131) in a Nonhuman Primate Cardiac Allotransplant Model

BACKGROUND: Specific blockade of T cell costimulation pathway is a promising immunomodulatory approach being developed to replace our current clinical immunosuppression therapies. The goal of this study is to compare results associated with 3 monoclonal antibodies directed against the CD40/CD154 T c...

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Publicado no:Transplantation
Main Authors: O'Neill, Natalie A., Zhang, Tianshu, Braileanu, Gheorghe, Sun, Wenji, Cheng, Xiangfei, Hershfeld, Alena, Laird, Christopher T., Kronfli, Anthony, Hock, Lindsay A., Dahi, Sia, Kubicki, Natalia, Sievert, Evelyn, Hassanein, Wessam, Cimeno, Arielle, Pierson, Richard N., Azimzadeh, Agnes M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568940/
https://ncbi.nlm.nih.gov/pubmed/28557955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0000000000001836
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