IP(3-4) kinase Arg1 regulates cell wall homeostasis and surface architecture to promote clearance of Cryptococcus neoformans infection in a mouse model

We previously identified a series of inositol polyphosphate kinases (IPKs), Arg1, Ipk1, Kcs1 and Asp1, in the opportunistic fungal pathogen Cryptococcus neoformans. Using gene deletion analysis, we characterized Arg1, Ipk1 and Kcs1 and showed that they act sequentially to convert IP(3) to PP-IP(5) (...

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Vydáno v:Virulence
Hlavní autoři: Li, Cecilia, Lev, Sophie, Desmarini, Desmarini, Kaufman-Francis, Keren, Saiardi, Adolfo, Silva, Ana P.G, Mackay, Joel P., Thompson, Philip E., Sorrell, Tania C., Djordjevic, Julianne T.
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2017
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5810508/
https://ncbi.nlm.nih.gov/pubmed/28976803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21505594.2017.1385692
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