IP(3-4) kinase Arg1 regulates cell wall homeostasis and surface architecture to promote clearance of Cryptococcus neoformans infection in a mouse model

We previously identified a series of inositol polyphosphate kinases (IPKs), Arg1, Ipk1, Kcs1 and Asp1, in the opportunistic fungal pathogen Cryptococcus neoformans. Using gene deletion analysis, we characterized Arg1, Ipk1 and Kcs1 and showed that they act sequentially to convert IP(3) to PP-IP(5) (...

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Detalhes bibliográficos
Publicado no:Virulence
Main Authors: Li, Cecilia, Lev, Sophie, Desmarini, Desmarini, Kaufman-Francis, Keren, Saiardi, Adolfo, Silva, Ana P.G, Mackay, Joel P., Thompson, Philip E., Sorrell, Tania C., Djordjevic, Julianne T.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5810508/
https://ncbi.nlm.nih.gov/pubmed/28976803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21505594.2017.1385692
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