TAB1-Induced Autoactivation of p38α Mitogen-Activated Protein Kinase Is Crucially Dependent on Threonine 185

p38α mitogen-activated protein kinase is essential to cellular homeostasis. Two principal mechanisms to activate p38α exist. The first relies on dedicated dual-specificity kinases such as mitogen-activated protein kinase kinase (MAP2K) 3 (MKK3) or 6 (MKK6), which activate p38α by phosphorylating Thr...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Thapa, Dibesh, Nichols, Charlie, Bassi, Rekha, Martin, Eva Denise, Verma, Sharwari, Conte, Maria R., De Santis, Vittorio, De Nicola, Gian F., Marber, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809688/
https://ncbi.nlm.nih.gov/pubmed/29229647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00409-17
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